Drug Standards
Medchemexpress LLC Celecoxib (Standard) | 169590-42-5 | 99.97% | C17H14F3N3O2S | 50 MG
Celecoxib (Standard) is the analytical standard of Celecoxib, intended for research and analytical applications. Celecoxib itself is a selective non-steroidal anti-inflammatory drug (NSAID) and a selective COX-2 inhibitor with an IC50 of 40 nM. The compound is of analytical standard grade, serving as a reference standard for assays and commonly utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for Celecoxib
- Intended for research and analytical applications
- Used as a reference standard supplied assay
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC Aminopterin | 54-62-6 | C19H20N8O5 | 25 MG
Aminopterin, also known as 4-Aminofolic acid, is a folic acid antagonist and a 4-amino derivative of folic acid. It functions by catalyzing the reduction of folic acid to tetrahydrofolic acid and competitively inhibiting dihydrofolate reductase (DHFR) with a Kᵢ of 3.7 pM. This compound exhibits both anticancer and immunosuppressive activities, making it useful in the treatment of pediatric leukemia.
- Folic acid antagonist
- Inhibits dihydrofolate reductase (DHFR)
- Exhibits anticancer activity
- Exhibits immunosuppressive activity
- Used for pediatric leukemia treatment
- IC50 value of 4.4 nM against CCRF-CEM cells
Medchemexpress LLC Celecoxib (Standard) | 169590-42-5 | 100.0% | C17H14F3N3O2S | 25 MG
Celecoxib (Standard) is the analytical standard of Celecoxib, intended for research and analytical applications. It functions as a selective non-steroidal anti-inflammatory drug (NSAID) and a selective COX-2 inhibitor.
- Analytical standard
- Used as a reference standard for assays
- IC50 of 40 nM for COX-2 inhibition
- Commonly employed in qualitative, quantitative, and methodological research
- Suitable for HPLC, GC, and MS experiments
Medchemexpress LLC Propyl gallate (Standard) | 121-79-9 | 212.20 | 50 MG
Propyl gallate (Standard) is the analytical standard of Propyl gallate. It is intended for research and analytical applications. Propyl gallate is a common food antioxidant that can inhibit the production of acrolein, glyoxal, and methylglyoxal. It also exhibits anti-inflammatory, antitumor, and cardioprotective activities.
- Used as an analytical standard for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Purity: 99.98%
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC Harpagoside | 19210-12-9 | 494.49 | 5 MG
Harpagoside can be obtained from *Harpagophytum procumbens*. It exhibits anti-inflammatory, anti-cancer, and protective activities. Harpagoside inhibits COX-1 and COX-2 activity, suppresses NO production, and inhibits HepG2 cell lipid polysaccharide expression, leading to anti-inflammatory and latent pain effects. It also has a protective and degenerative effect on β-oxidation (Aβ).
- Anti-inflammatory activity.
- Anti-cancer activity.
- Protective activity.
- Inhibitory effect on COX-1 and COX-2.
- Suppresses NO production.
- Inhibits HepG2 cell lipid polysaccharide expression.
- Potential neuroprotective effects against Aβ intoxication in an Alzheimer's disease model.
Medchemexpress LLC Octyl gallate | 1034-01-1 | MFCD00002197 | 282.33 | 25 MG
Octyl gallate, also known as Progallin O, is a derivative of gallic acid recognized for its diverse biological activities. It is frequently employed as a food additive due to its potent antioxidant and antimicrobial properties. Research indicates its promising effectiveness against a broad spectrum of microorganisms, including both Gram-positive and Gram-negative bacteria. Furthermore, it has demonstrated significant antiviral effects against viruses such as HSV-1, vesicular stomatitis virus (VSV), and poliovirus, as well as notable antifungal activity.
- Acts as a powerful antioxidant.
- Exhibits broad-spectrum antibacterial activity.
- Shows selective antiviral properties.
- Possesses antifungal effects.
- Commonly used as a food additive.
Medchemexpress LLC Propyl gallate (standard) | 121-79-9 | MFCD00002196 | 212.20 | 100 MG
Propyl gallate (Standard) is the analytical standard of Propyl gallate, intended for research and analytical applications. It functions as a common food antioxidant and can inhibit the production of acrolein, glyoxal, and methylglyoxal. Additionally, it exhibits anti-inflammatory, antitumor, and cardioprotective activities.
- Analytical standard for Propyl gallate
- Intended for research and analytical applications
- Common food antioxidant
- Inhibits production of acrolein, glyoxal, and methylglyoxal
- Exhibits anti-inflammatory activities
- Exhibits antitumor activities
- Exhibits cardioprotective activities
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC Propyl gallate | 121-79-9 | 212.20 | 25 MG
Propyl gallate (Standard) is the analytical standard of Propyl gallate, intended for research and analytical applications. It is a common food antioxidant and can inhibit the production of acrolein, glyoxal, and methylglyoxal.
- Analytical standard for Propyl gallate.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Common food antioxidant.
- Inhibits the production of acrolein, glyoxal, and methylglyoxal.
- Exhibits anti-inflammatory, antitumor, and cardioprotective activities.
Medchemexpress LLC Carbocisteine | 638-23-3 | 98.0% | 1 G
Carbocisteine is an orally active mucolytic agent. It attenuates the phosphorylation of NF-κB p65 and ERK1/2, modulates Nrf2/HO-1 and NFκB interplay, and inhibits apoptosis. It is used in chronic obstructive pulmonary disease (COPD) research.
- Orally active mucolytic agent
- Attenuates the phosphorylation of NF-κB p65 and ERK1/2
- Modulates Nrf2/HO-1 and NFκB interplay
- Inhibits apoptosis
- Used in chronic obstructive pulmonary disease (COPD) research
Medchemexpress LLC Chitosan | 9012-76-4 | ≥85.0% | 1 G
Chitosan (Deacetylated chitin) (≥85% deacetylated, viscosity>90 mPa.s, MW 15000) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. It is a polycationic linear polysaccharide with non-toxicity, low allergenicity, biocompatibility, biodegradability, and has antitumor, antibacterial, antifungal, and antioxidant activities.
- Polycationic linear polysaccharide
- Non-toxicity
- Low allergenicity
- Biocompatibility
- Biodegradability
- Antitumor activity
- Antibacterial activity
- Antifungal activity
- Antioxidant activity
Medchemexpress LLC Bromfenac sodium | 91714-93-1 | 99.9% | 200 MG
Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. It can be used in ocular inflammation research.
- Potent and orally active inhibitor of COX
- IC50s of 5.56 nM for COX-1 and 7.45 nM for COX-2
- Can be used in ocular inflammation research
- Solid appearance
- Light yellow to yellow color
Medchemexpress LLC Isosorbide (D-Isosorbide; Dianhydro-D-glucitol) | 652-67-5 | 98.8% | 1 ML
Isosorbide (D-Isosorbide) is an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain). It is also an oral hyperosmotic diuretic.
- Orally active vasodilating agent.
- Useful for the research of heart failure and angina (chest pain).
- Functions as an oral hyperosmotic diuretic.
![Medchemexpress LLC 2,4-Pyrimidinediamine, 5-[(3,4-dimethoxyphenyl)methyl]- | 5355-16-8 | 99.8% | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000411265-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2,4-Pyrimidinediamine, 5-[(3,4-dimethoxyphenyl)methyl]- | 5355-16-8 | 99.8% | 500 MG
Diaveridine is an antibacterial agent and a dihydrofolate reductase (DHFR) inhibitor, demonstrating a Ki of 11.5 nM for the wild-type DHFR. For research use only, this product is not intended for patient use. In vitro treatments with Diaveridine for 90 minutes show a strong bactericidal effect on S. typhimurium TA1535, with no bacterial growth observed at concentrations of 10 μg/mL or more.
- Dihydrofolate reductase (DHFR) inhibitor
- Antibacterial agent
- Ki of 11.5 nM for wild-type DHFR
- Strong bactericidal effect on S. typhimurium TA1535 at ≥ 10 μg/mL
Medchemexpress LLC Neostigmine methyl sulfate | 51-60-5 | 98.9% | 100 MG
Neostigmine methyl sulfate (Standard) serves as an analytical standard, designed for research and analytical applications. This reference standard assay is widely utilized in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Intended for research and analytical applications.
- Functions as a reference standard supplied assay.
- Used in qualitative, quantitative, and methodological research.
- Suitable for techniques including HPLC, GC, and MS.
Medchemexpress LLC Isosorbide | 652-67-5 | 98.8% | 500 G
Isosorbide is an orally active vasodilating agent used in the research of heart failure and angina (chest pain). It also acts as an oral hyperosmotic diuretic.
- Orally active vasodilating agent
- Used for research of heart failure and angina (chest pain)
- Oral hyperosmotic diuretic
- Appearance: solid, white to off-white
- Molecular weight: 146.14
- Formula: C6H10O4
- Soluble in H2O and DMSO